Why splenomegaly in infective endocarditis

In attempting to answer this question we shall consider: the volume of the normal spleen; the means of detecting moderate splenomegaly; the circulation of the spleen, and the evidence of pathologist and clinician, and finally see whether well taken hospital histories reflect the conclusions otherwise derived. The normal spleen varies from to 20 gm. The spleen is relatively smaller in women, and tends to atrophy. Coronavirus Resource Center. Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy Continue.

Twitter Facebook. This Issue. Lymphadenopathy may be present due to an underlying lymphoproliferative process or associated infection. Chronic liver disease signs may be present as portal hypertension is a common cause of splenomegaly. Look for stigmata of infective endocarditis such as Oslers nodes, janeway lesions, finger clubbing and splinter haemorrhages.

Causes: It is often helpful to break causes of splenomegaly down into those which cause massive, moderate or mild splenomegaly. Causes of Massive splenomegaly include : myeloproliferative disorders such as chronic myeloid leukaemia, acute myeloid leukaemia and myelofibrosis.

Causes of Mild splenomegaly include: myelo and lymphoproliferative disorders, portal hypertension, infections such as infective endocarditis, Epstein Barr virus infection and viral hepatitis, haemolytic anaemia and autoimmune causes e. Download PDF. This item has received. Article information. TABLE 1. TABLE 6. TABLE 7.

Show more Show less. Introduction and objectives. Among the complications of infective endocarditis, systemic enbolisms are an ominous prognostic sign. The aim of the present study was to compare the demographic, clinical, microbiologic and echocardiographic features of episodes of endocarditis accompanied and unaccompanied by embolisms in the spleen, kidney or liver.

We also assessed the prognostic impact of these embolisms. Material and method. Prospective, multicenter clinical cohort study. We analyzed consecutive episodes of left-sided infective endocarditis in patients. Of these, 34 were located in the spleen, 5 in the kidney and 2 in the liver.

Some forms of clinical presentation predominated in group I, e. Staphylococcus aureus and enterococci were more commonly isolted in group I. Detection of vegetations by transesophageal echocardiography was more frequent in group I, and they were larger than vegetations in group II. Hepatosplenic and renal embolisms were not independently associated with the need for cardiac surgery or death. The clinical presentation of these episodes has characteristic features.

Vegetations are larger than in episodes without these embolism. Hepatosplenic and renal embolisms do not increase neither the need of cardiac surgery nor the risk of death.. Palabras clave:. Full Text. Definition of Terms The patients were divided into two groups: group I patients had embolisms in the liver, spleen or kidney, group II patients had no embolisms in these organs. Significance was set at P RESULTS Three hundred and thirty eight episodes of left endocarditis were analyzed involving native valves, involving prosthetic valves.

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